The Blue Hens have appeared in the NCAA tournament five times, with their 2013 Sweet Sixteen appearance being their best showing. In the 2011–12 and 2012–13 seasons, they went undefeated in CAA play, going 18–0 twice. They won their first ever NCAA Tournament game in 2012, beating Little Rock 73–42 before losing in the ensuing round to Kansas 70–64. They made the regional semifinals in the 2013 NCAA Division I women’s basketball tournament after beating West Virginia 66–53 and North Carolina 78–69 before losing to Kentucky 69–62. They also appeared in the WNIT Tournament nine times, with their 2021 semifinal appearance and Charlotte Regional Championship being their best.