Thomas was a standout four-year starter at Mississippi State University.

Thomas was the eighth freshman in the 25-year history of Kodak All-America honors to earn the award and first Lady Bulldog to be named a Kodak All-American. She went on to become just the sixth player in women’s basketball history to be a four-time Kodak All-American. She left her mark in the SEC as well, becoming the first player in the conference to lead the league in scoring all four years of her career. Thomas was a three-time finalist for the Naismith Award and she was also a four-time first-team all-SEC and AP all-SEC selection. Thomas was a finalist in 2003 for Margaret Wade Trophy given each season to the top female college player. Diana Taurasi won the Wade Trophy in 2003.

Thomas is the all-time leading scorer at Mississippi State, for either men or women, with 2,981 career points. She holds the Lady Bulldog records for field goals made, field goals attempted, field goal percentage, free throws made, free throws attempted, free throw percentage, rebounds, and blocked shots.

In addition to her numerous all-America honors, Thomas was named the Lowe’s Senior CLASS Award winner, 2003 Mississippi Amateur Athlete of the Year, and 2003 SEC Female Athlete of the Year. Upon graduation, she became the first athlete from the state of Mississippi to be taken as a top pick in a professional draft, going No. 1 to the Cleveland Rockers in the 2003 WNBA Draft.