The 1941 Duquesne Dukes football team finished the season with an undefeated record of 7-0-1. Led by head coach Elmer Layden, the team was considered one of the best in the school’s history.

The Dukes opened the season with a 13-6 win over Villanova and went on to defeat Temple, Saint Vincent, Carnegie Tech, Boston College, and West Virginia. They tied with Duquesne’s cross-town rival, the University of Pittsburgh, in the final game of the season.

The team was known for its strong defense, which allowed only 33 points throughout the entire season. Several players from the team went on to play professionally in the NFL, including Bill Daddio, Jack Doyle, and Tony Kaska.

The 1941 Duquesne Dukes football team was posthumously inducted into the Duquesne University Athletics Hall of Fame in 1989.